Introduction to a Revolutionary Technology
In a significant breakthrough, researchers at Monash University have developed a groundbreaking microchip Read More
The Science Behind the Microchip
The new microchip, unveiled in research published in the Human Reproduction journal, leverages light-emitting technology to measure the energy output of embryos. This metric is crucial for determining embryo health, making it a key factor in selecting the most viable candidates for implantation. The collaboration between reproductive science experts at the University of New South Wales (UNSW) and engineers at Monash University has focused on integrating advanced imaging capabilities into the microchip, initially tested on live mouse embryos.
Expert Insights
Dr. Fabrizzio Horta, a senior lecturer at UNSW and a pivotal figure in the research team, emphasized the potential impact of this technology. “By harnessing sophisticated and advanced technology on this microchip, we can enhance our understanding of embryo viability at a significantly reduced cost,” stated Dr. Horta, whose previous affiliation with Monash University played a crucial role in the project’s inception.
A Closer Look at the Technology
The novel device, about the size of the kangaroo head on an Australian $1 coin, uses microlenses to illuminate individual embryos, measuring their energy output without inflicting damage. This non-invasive method contrasts sharply with the current practices involving embryo biopsies for genetic testing, which are not only costly and time-consuming but also pose risks to the embryos.
Current Practices and Innovations
Embryo selection in IVF clinics currently depends heavily on the subjective assessment of specialists using standard optical microscopes. The reliance on operator expertise and expensive genetic testing often extends the IVF process, compounding the emotional and financial strain on couples.
The Future of IVF
Dr. Horta highlighted the efficiency of the new device, saying, “The device enables us to reconstruct high-resolution images of an embryo’s metabolic activity, which are indicative of genetic or metabolic abnormalities.” He pointed out that the closest existing technologies are complex research systems costing around $1 million and unsuitable for clinical use. In contrast, the microchip could be produced at a fraction of the cost, paving the way for its integration into clinical IVF workflows and potentially benefiting research and animal industries.
Moving Forward
The technology has already been submitted for patent filing by Monash University, reflecting its innovative design and scalability. The research team is currently exploring investment opportunities and the possibility of launching a spinout company to commercialize the microchip globally, aiming to make IVF a less daunting challenge for millions of couples worldwide.
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Reference article – https://www.unsw.edu.au/news/2024/11/the-new-microchip-that-could-boost-ivf-success-rates